Echinacea | Common colds, wounds and burns, UTIs, coughs and URIs, bronchitis | Hepatotoxicity; potentiation of hepatotoxic effects of amiodarone, ketoconazole, methotrexate, anabolic steroids; may decrease effects of corticosteroids and cyclosporine; anaphylaxis |
Ephedra | Dietary aid for weight loss, antitussive actions, increased energy | Potential interactions with cardiac glycosides, MAOIs, oxytocin, guanethidine, MI, stroke, hypertension, tachycardia, arrhythmias |
Feverfew | Migraines, antipyretic | Inhibit platelet activity, rebound headache |
Garlic | Lowering lipids, vasodilatation, antihypertensive, antiplatelet effects, antioxidant, cardiovascular disease prevention | Potentiate effects of warfarin, heparin, aspirin, leading to abnormal bleeding time; risk for perioperative hemorrhage |
Ginger | Antiemetic, antivertigo | Potentiate anticoagulant effects of drugs, inhibits thromboxane synthetase |
Ginkgo biloba | Antioxidant, circulatory stimulation, vertigo, memory loss, sexual dysfunction, tinnitus, intermittent claudication | Potentiate anticoagulant effects of drugs (ASA, NSAIDs, warfarin, heparin); may decrease effectiveness of anticonvulsant drugs, may lower seizure threshold in patients taking TCAs; spontaneous hyphema and intracranial bleeds |
Ginseng | Enhance energy levels, antioxidant, aphrodisiac, promote diuresis, facilitate digestion | Sleepiness, hypertonia, edema, hypoglycemia, tachycardia, hypertension, mania in patients taking MAOIs, inhibition of platelet aggregation, epistaxis, Stevens–Johnson syndrome |
Goldenseal | Diuretic, laxative, anti-inflammatory | Paralysis, hypertension, electrolyte abnormalities |
Kava-kava | Anxiolytic, skin disorders, antiepileptic, antipsychotic | Potentiate effects of barbiturates, benzodiazepines, and ethanol; increased suicide risk, can inhibit norepinephrine, decreased MAC requirements; hepatotoxicity, hallucinations |
Licorice | Gastritis, gastric and duodenal ulcers, cough and bronchitis | Hypertension, hypokalemia, edema, renal insufficiency, hypertonia, can worsen chronic liver diseases |
Saw palmetto | Antiandrogenic, treatment for benign prostatic hyperplasia | Additive effects with other hormone replacement therapy, headaches, GI discomfort |
St. John’s wort | Depression, anxiety, sleep-related disorders, vitiligo | Interact with MAOIs, prolonged effects of anesthesia, photosensitivity, possible serotoninergic syndrome with patients taking SSRIs, restlessness, dizziness, fatigue, nausea |
Valerian | Anxiolytic, sedative | Potentiate effects of barbiturates, benzodiazepine-like withdrawal syndrome, prolonged effects of anesthesia |