Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content +++ CLASSIFICATION OF DIFFERENT STAGES OF DIASTOLIC DYSFUNCTION ++ Table Graphic Jump Location|Download (.pdf)|Print Normal Impaired Relaxation Pseudonormal Restrictive Filling TMF E/A ≥0.8 ≤0.8 0.8–2 ≥2 DT (ms) 150–220 >200 150–220 <160 IVRT (ms) 60–100 >100 60–100 <60 PVF PV-S/PV-D >1 >1 <1 <1 PV-AR (cm/s) <35 <35 >35 >35 ARdur-Adur (ms) <30 <30 >30 >30 Vp (cm/s) >55 <45 <45 <45 E' (cm/s) >8 (septal) >8 (septal) <8 (septal) <8 (septal) >10 (lateral) >10 (lateral) <10 (lateral) <10 (lateral) Average* E/E' <10 <10 10–14 >14 *Average of septal and lateral velocities. Abbreviations: TMF, transmitral flow; E, early filling peak velocity; A, atrial contraction peak velocity; DT, deceleration time of E wave; IVRT, isovolumic relaxation time; PV-S, peak velocity of systolic component; PV-D, peak velocity of diastolic component; PV-AR, peak velocity of atrial reversal flow; PV-ARdur, duration of atrial reversal flow; Adur, duration of A wave; PVF, pulmonary venous flow; E', early diastolic velocity of the mitral annulus by tissue Doppler imaging; Vp, propagation velocity. +++ ALGORITHM FOR GRADING DIASTOLIC DYSFUNCTION ++ FIGURE (A) Algorithm for diagnosis of left ventricular (LV) diastolic dysfunction. LV diastolic function is normal if more than half of the available parameters do not meet the cutoff values for identifying abnormal function. LV diastolic dysfunction is present if more than half of the available parameters meet these cutoff values. The study is inconclusive if half of the parameters do not meet the cutoff values (B) Algorithm for estimation of LV filling pressures and grading LV diastolic function in patients with diastolic dysfunction. (Modified with permission from Nagueh SF, Smiseth OA, Appleton CP, et al: Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging, J Am Soc Echocardiogr 2016 Apr;29(4):277–314.) Graphic Jump LocationView Full Size||Download Slide (.ppt) +++ EFFECT OF AGE ON DOPPLER-DERIVED DIASTOLIC MEASUREMENTS ++ ++ Table Graphic Jump Location|Download (.pdf)|Print Age Group (years) Doppler Parameter Measurement <20 21–60* >60 Transmitral low IVRT (ms) 50 ± 9 67–74 87 ± 7 E/A ratio 1.9 ± 0.5 1.5–1.3 1.0 ± 0.2 DT (ms) 142 ± 19 166–181 200 ± 29 A dur (ms) 113 ± 17 127–133 138 ± 19 Pulmonary vein flow S/D ratio 0.8 ± 0.18 1.0–1.2 1.4 ± 0.5 Ar (cm/s) 16 ± 10 21–23 25 ± 9 Ar dur (ms) 66 ± 39 96–112 113 ± 30 Lateral annulus tissue velocity E′ (cm/s) 21 ± 3.8 20–16 13 ± 3.5 E′/A′ ratio 3.1 1.9–1.5 0.9 ± 0.4 Values are expressed as mean ± standard deviation.*For the age group 21–60, values are expressed as range of means. Abbreviations: A', late lateral annulus tissue velocity; A, late transmitral ... Your Access profile is currently affiliated with [InstitutionA] and is in the process of switching affiliations to [InstitutionB]. Please select how you would like to proceed. Keep the current affiliation with [InstitutionA] and continue with the Access profile sign in process Switch affiliation to [InstitutionB] and continue with the Access profile sign in process Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Error: Incorrect UserName or Password Username Error: Please enter User Name Password Error: Please enter Password Sign in Forgot Password? Forgot Username? Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free profile for additional features.