Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content +++ Abbreviations ++ ACT: Activated clotting time Table 1A and B: ACS: Acute coronary syndrome Afib: Atrial fibrillation Anesth.: Anesthesia aPTT: Activated partial thromboplastin time ASA: Acetylsalicylic acid ATE: Arterial thromboembolism BMS: Bare metal stent COX: cyclooxygenase CrCl: Creatinine clearance CV: CHA2DS2-VASc CVA: Cerebral vascular accident CYP3A4: Cytochrome P450 3A4 DES: Drug eluting stent DVT: Deep venous thrombosis GP IIb-IIIa: glycoprotein IIb-IIIa HB: HAS-BLED score ICD: implantable cardioverter defibrillator INR: International normalized ratio IV: Intravenous LMWH: Low molecular weight heparin NOACs: New oral anticoagulants OBR: Intra operative bleeding risk Prim.: primary PCI: Percutaneous coronary intervention PE: Pulmonary embolism P-gp: P-glycoprotein PT: Prothrombin time Prev.: prevention PO: Per Os RA: Regional anaesthesia SC: Subcutaneous Sec.: secondary TER: Thrombo embolic risk TIA: Transient ischemic attack UFH: Unfractionated heparin VKA: Vitamin K antagonist VTE: Venous thromboembolism ++Table Graphic Jump LocationTable 1–1A.Overview of antiplatelet agents and anticoagulants with clinically useful information about dosage and perioperative management of patients using this type of drug. The overview was composed from a perspective of medical practice in western europe (Belgium).View Table||Download (.pdf) Table 1–1A. Overview of antiplatelet agents and anticoagulants with clinically useful information about dosage and perioperative management of patients using this type of drug. The overview was composed from a perspective of medical practice in western europe (Belgium). Product (T½ in Hours) Brand Name Normal Dose ⊗ ◉ Bridging Comments Concerning RA COX inhibitors (ASA) PO Aspirin (3) Asaflow® Prim. prevention: 80 mg 1x/d Sec. prevention: 80 mg 1x/d 5 d do not stop 24 h 24 h Don’t bridge with LMWH Spinal anesthesia: OK Epidural anesthesia: OK Aggrenox® = ASA + Dipyridamole ≈ ASA P2Y12 inhibitors PO Clopidogrel (7) Ticlopidine (12) Prasugrel (7) Ticagrelor (7) Plavix® Ticlid® Efient® Brilique® Prim. prevention: No indication Sec. prevention: 75 mg po 1x/d 250 mg po 2x/d 10 mg po 1x/d 90 mg po 2x/d 7 d 10 d 10 d 7 d 24 h 24 h 24 h 24 h Don’t bridge with LMWH Asaflow® 80 mg po 1x/d Asaflow® 80 mg po 1x/d Asaflow® 80 mg po 1x/d Asaflow® 80 mg po 1x/d Neuraxial anesthesia: NO Combi-therapie: ASA x P2Y12 (see Table 1-1B) GP IIb-IIIa inhibitors Abciximab (20’) Eptifibatid (2,5) Tirofiban (2) Reopro® Integrilin® Aggrastat® iv iv iv 48 h 12 h 12 h 4 h 4 h 4 h Don’t bridge with LMWH Neuraxial anesthesia: NO Platelet count ≥ 70×109/L VKA PO Acenocoumarol (8) Warfarine (40) Fenprocoumol (120) Sintrom® Marevan® Marcoumar® 1-8 mg po 1x/d 1,5-5 mg po 1x/d 1,5-6 mg po 1x/d 4 d 7 d 10 d 72 h 72 h 72 h LMWH according to ... Your Access profile is currently affiliated with [InstitutionA] and is in the process of switching affiliations to [InstitutionB]. Please select how you would like to proceed. Keep the current affiliation with [InstitutionA] and continue with the Access profile sign in process Switch affiliation to [InstitutionB] and continue with the Access profile sign in process Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Error: Incorrect UserName or Password Username Error: Please enter User Name Password Error: Please enter Password Sign in Forgot Password? Forgot Username? Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free profile for additional features.