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The first edition of Goodman & Gilman's The Pharmacological Basis of Therapeutics was published in 1941. Medicine has changed dramatically since then; so, too, has the delivery of information. The editors of the online version of 12th edition of Goodman & Gilman are hoping to be at the forefront of publishing technology in a project to enhance the premier text in pharmacology and bring it to your desktop.

We hope to bring not just the text of the book but to enhance the text with additional features. The production of on-line resources for Goodman & Gilman will be guided by three complementary priorities:

  1. To provide regular updates, particularly in areas of pharmacology and therapeutics where significant advances in basic or clinical research have occurred since publication of the printed version

  2. To provide faculty and students with high-quality electronic resources to enhance teaching and learning of pharmacology

  3. To provide comprehensive search results that allow users quick access to required content

We are currently working on the following online resources to enhance the 12th edition of Goodman & Gilman:

  • Updates: Regular updates, including new chapter content, a Clinical Pharmacist's Corner that discusses newly approved drugs or new therapeutic uses of approved drugs, and pieces that focus on emerging areas of pharmacological interest

  • Grand Rounds: Occasional webcasts of lectures in areas of therapeutic importance by authorities

  • Multimedia Content: To complement the text, we have started an ongoing series of interactive, animated versions of some of the more important figures from Goodman & Gilman, which are useful for interactive self-study by students

The Editors of Goodman & Gilman welcome your thoughts on improvements and corrections to the text, as well as suggestions and submissions for online updates. If you are a pharmacologist, pharmacist, physician, or medical scientist and you are interested in contributing an update, please submit a request through our feedback form.


The ENIAC (Electronical Numerical Integrator and Computer; circa 1945) was the first electronic computer. The invention of Dr. J. W. Mauchly and Mr. J. Presper Eckert, it containied close to 18,000 vacuum tubes, occupied a room 30 by 50 feet, weighed 30 tons and cost of more than $486,000. It was used at the War Department's Ballistics Research Laboratory to calculate artillery trajectories. (U.S. Army Photo, courtesy of and

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1st Edition Table of Contents


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