APPENDIX 1: PEDIATRIC ANESTHESIOLOGY SUGGESTED DRUG DOSAGES

Atropine: 0.01-0.03 mg/kg IM, IV, ET, IC, IO

Sodium bicarbonate: 1-2 mEq/kg (0.3 × kg × BE) IV, IC, IO

Calcium chloride 10-30 mg/kg IV, IC slowly (max 1 g/dose)

Calcium gluconate 60-100 mg/kg IV, IC (max 2 g/dose)

Dextrose 0.5-1 g/kg IV = 1-2 mL/kg D₅₀; or 2-4 mL/kg D₂₅W or 5-10 mL/kg D₁₀W or 10-20 mL/kg D₅NS

Diltiazem (Cardizem): 0.25 mg/kg over 2 min; may repeat in 15 min @ 0.35 mg/kg over 2 min

Ephedrine: 0.2-0.3 mg/kg/dose

Epinephrine 10 μ/kg IV, IC, IO; ET = 100 μg/kg

Lidocaine: 1 mg/kg IV, IC, ET, IO

Lipid emulsion (Intralipid): 20% 1.5 mL/kg over 1 min × 3 prn, 0.25 mL/kg/min then 0.5 mL/kg/min if hypotensive

V-Fib: 2 J/kg then 4 J/kg (defibrillation = unsynchronized) using the largest paddles that fit

Synchronized cardioversion: 0.5-1 then 2 J/kg

Adenosine: 0.1 mg/kg IV push (max 6 mg); repeat 0.2 mg/kg (max 12 mg)

Amiodarone: V Fib: 5 mg/kg IV load over 30 sec (max 300 mg)

SVT: 5 mg/kg over 10 min × 5 doses; non-PVC container

Digoxin: initial load 4-25 μg/kg IV Maintenance 5-10 μg/kg/dose BID

IV dose = 2/3 PO dose

Diltiazem: 0.25 mg/kg over 2 min; may repeat in 15 min @ 0.35 mg/kg over 2 min

Dopamine, dobutamine: 2-20 μg/kg/min

Ephedrine: 0.2-0.3 mg/kg/dose

Epinephrine, isoproterenol, norepinephrine: 0.05-1 μg/kg/min

Esmolol: 0.5 mg/kg bolus over 1 min; Maintenance: 50-300 μg/kg/min

Lidocaine: 1-2 mg/kg/dose IV 20-50 μg/kg/min (adult dose 1-4 mg/min)

Magnesium sulfate for torsades de pointes: 25-50 mg/kg (max 2 g) over 10-20 min

Milrinone: 20-50 μg/kg load; maintenance: 0.3-0.7 μg/kg/min

Nitroglycerin: 0.5-5 μg/kg/min

Nitroprusside: 0.5-10 μg/kg/min

PGE₁ = Alprostadil: 0.05-0.1 μg/kg/min

Phenylephrine: 0.5-10 μg/kg/min; 1 μg/kg bolus

Procainamide: 3-6 mg/kg (max 100 mg each dose) over 5 min × 3 q 5-10 min Maintenance: 20-80 μg/kg/min (adult 1-4 mg/min)

Propranolol: 0.05-0.15 mg/kg IV slowly (max 5 mg)

Vasopressin: Mix 10 U in 50 mL so 1 mL = 0.2 U

hypotension: 0.0005-0.002 U/kg/min

GI bleed: 0.002-0.005 U/kg/min

Verapamil: 0.05-0.2 mg/kg IV over 2 min (max 5 mg)

Cisatracurium: 0.1-0.2 mg/kg/dose IV; lasts 15-45 min

Pancuronium: 0.1 mg/kg/dose IV; lasts 1-2 h

Rocuronium: 0.4-1.0 mg/kg/dose IV; 0.6 mg/kg/h

Succinylcholine: 1-2 mg/kg IV; 4 mg/kg IM; consider giving atropine first

Vecuronium: 0.1 mg/kg/dose IV; 60 μg/kg/h

Chloral ...