RT Book, Section A1 Yosaitis, John A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1102570257 T1 Blood Type, Screen, and Crossmatch T2 Anesthesiology Core Review: Part One Basic Exam YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 9780071821377 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1102570257 RD 2024/04/19 AB The leading cause of death from hemolytic transfusion reactions is transfusion of the incorrect ABO group blood. The ABO system is by far the most significant of all the antigen–antibody groups in transfusion practice. The ABO classification is the only blood group system in which patients have antibodies to antigens that have never been present in their system. In other blood group systems there needs to be an exposure to the antigen through prior transfusion or pregnancy.