RT Book, Section A1 Freeman, Brian S. A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1102569495 T1 Baroreceptor Function T2 Anesthesiology Core Review: Part One Basic Exam YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 9780071821377 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1102569495 RD 2024/04/19 AB Baroreceptors are specialized sensory neurons that enable the central nervous system (CNS) to maintain short-term control of blood pressure. These mechanoreceptors participate in a reflex (baroreceptor reflex, carotid sinus reflex) that regulates the mean arterial pressure, relatively constant at a preset value, usually around 100 mm Hg. In this negative feedback loop, a rise in blood pressure from baseline results in rapid signals from the baroreceptors to the CNS which then reduces MAP back down to normal level through the autonomic nervous system. A slight change in pressure causes a strong change in the baroreflex signal to readjust arterial pressure back toward normal. The arterial baroreceptor reflex serves as short-term blood pressure buffering system in response to relatively abrupt changes in blood volume, cardiac output, or peripheral resistance, such as during daily activities (posture changes, exercise) and during surgery (anesthesia, hemorrhage).