RT Book, Section A1 Nishanian, Ervant A1 Shaefi, Shahzad A2 Atchabahian, Arthur A2 Gupta, Ruchir SR Print(0) ID 57261762 T1 Chapter 91. Thoracoabdominal Aneurysm T2 The Anesthesia Guide YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-176049-2 LK accessanesthesiology.mhmedical.com/content.aspx?aid=57261762 RD 2024/04/23 AB Often associated with HTN, atherosclerosis, and connective tissue disorders such as Marfan syndromeBest surgical series has 10% mortalityHigh risk of rupture along with aortic dissection. Untreated aortic dissection carries a 25–35% mortality within the first few daysComorbiditiesPVDCADHTNChronic obstructive pulmonary disease (COPD) (smokers)Renal impairment (independent predictor of postop renal failure and mortality)Anticipate potential for rapid large blood loss and hemodynamic shifts. Successful outcome requires maintenance of adequate cardiac output and flow to vital organs including the spinal cord while avoiding hypertension and aortic ruptureRisk of paraplegia ≥3.5% blood as supply to the anterior spinal artery involved. Techniques to reduce incidence of paraplegia include: Epidural cooling of the spinal cord during surgeryCerebrospinal fluid drainageReimplantation of intercostal arteriesSSEP monitoringProvision of distal aortic perfusion during surgery with the use of atriofemoral (left atrium) bypass to the distal aortaEndovascular repairs are possible in patients that have appropriate anatomy. However, be prepared to convert to open procedure