RT Book, Section A1 Parikh, Rita A2 Atchabahian, Arthur A2 Gupta, Ruchir SR Print(0) ID 57261315 T1 Chapter 68. Heparin-Induced Thrombocytopenia T2 The Anesthesia Guide YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-176049-2 LK accessanesthesiology.mhmedical.com/content.aspx?aid=57261315 RD 2024/04/19 AB Type 1: Isolated HIT develops early in heparin therapy and is benign. No resultant bleeding or thrombotic complications. Not mediated by the immune system: passive heparin binding to platelets resulting in a modest shortening of the platelet life span. The platelet count rarely falls below 100 × 109/LType 2: Heparin-induced thrombocytopenia and thrombosis syndrome (HITTS) is associated with severe thrombocytopenia and paradoxically thrombotic episodes instead of hemorrhagic complications. Occurs in patients receiving heparin for more than 5 days; may occur within 1 day if prior heparin therapy exposure <100 days