RT Book, Section
A1 Wu, Jennifer
A1 Atchabahian, Arthur
A2 Atchabahian, Arthur
A2 Gupta, Ruchir
SR Print(0)
ID 57260602
T1 Chapter 25. Diabetes Mellitus
T2 The Anesthesia Guide
YR 2013
FD 2013
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-176049-2
LK accessanesthesiology.mhmedical.com/content.aspx?aid=57260602
RD 2024/04/24
AB Table  Graphic  Jump  Location|Download  (.pdf)|PrintPathophysiologyType  1Type  2GestationalIncidence0.4%  of  population  in  20057%  of  population  in  20054%  of  pregnant  womenOnsetTypically  before  age  30Increases  with  increasing  ageRisk  factorsGenetics,  environmentalObesity,  geneticsObesityPathophysiologyAutoimmune  destruction  of  beta  cells,  resulting  in  insulin  deficiencyInsulin  resistance,  increased  glucose  productionSomatomammotropin  causes  insulin  resistanceComplicationDiabetic  ketoacidosis  (DKA)Hyperglycemic–hyperosmolar  nonketotic  comaCongenital  abnormalities,  stillbirthOutcomeOcular:  cataracts,  retinopathy,  blindnessVascular:  coronary  artery  disease,  peripheral  vascular  diseaseRenal:  leading  cause  of  renal  failure  in  the  United  StatesNeurologic:  peripheral  neuropathy,  autonomic  neuropathyGI:  delayed  gastric  emptyingNB:  HTN  accelerates  microangiopathy  and  macroangiopathyMost  resolve  postpartum30–60%  chance  of  developing  diabetes  postpregnancy  later  in  life