RT Book, Section A1 Dewaele, Steven A1 Santos, Alan C. A2 Hadzic, Admir SR Print(0) ID 55901490 T1 Chapter 9. Toxicity of Local Anesthetics T2 Hadzic's Peripheral Nerve Blocks and Anatomy for Ultrasound-Guided Regional Anesthesia, 2e YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-154963-9 LK accessanesthesiology.mhmedical.com/content.aspx?aid=55901490 RD 2024/04/19 AB Systemic toxicity of local anesthetics can occur after administration of an excessive dose, with rapid absorption, or because of an accidental intravenous injection. The management of local anesthetic toxicity can be challenging, and in the case of cardiac toxicity, prolonged resuscitation efforts may be necessary.1,2 Therefore, understanding the circumstances that can lead to systemic toxicity of local anesthetics and being prepared for treatment is essential to optimize the patient outcome.