RT Book, Section A1 Liu, Qing A1 Gold, Michael S. A2 Hadzic, Admir SR Print(0) ID 1141738309 T1 Neurobiologic Mechanisms of Nociception T2 Hadzic's Textbook of Regional Anesthesia and Acute Pain Management, 2e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071717595 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1141738309 RD 2024/04/24 AB Optimal postoperative pain management is a clinical priority because poorly managed pain may delay functional recovery from surgery and /or lead to chronic pain.1 Nevertheless, despite considerable effort to improve postoperative pain management, one third of patients continue to suffer from moderate to severe pain.2 The lack of consistently effective analgesics devoid of deleterious consequences remains one of the main causes of the inadequacy of postoperative pain management. Therefore, identification of novel therapeutic targets and more effective management strategies remain high priorities in pain research.