RT Book, Section
A1 Sedghi, Kia
A1 Go, Ramon
A1 Berger, Jeffrey
A2 Freeman, Brian S.
A2 Berger, Jeffrey S.
SR Print(0)
ID 1135741724
T1 Ion Channel Myopathies
T2 Anesthesiology Core Review: Part Two Advanced Exam
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9781259641770
LK accessanesthesiology.mhmedical.com/content.aspx?aid=1135741724
RD 2024/04/19
AB Ion  channel  myopathies  consist  of  disorders  featuring  paralysis  and  hypotonia.  Unlike  myotonic  dystrophy  or  other  causes  of  myopathies,  ion  channel  myopathies  are  a  group  of  genetic  defects  in  sodium,  chloride,  and  calcium  ion  channels  that  are  present  in  the  myocyte  membranes,  leading  to  myotonia.  Myotonic  disorders  have  multiple  etiologies  and  some  disorders  may  be  considered  a  channelopathy  if  ion  channel  conductance  is  the  culprit  in  the  disease,  but  the  most  common  cause  myotonia  is  not  due  to  an  ion  channelopathy  but  a  defect  in  the  protein  kinase  production.