RT Book, Section A1 Freeman, Brian S. A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1135741690 T1 Myasthenic Syndromes T2 Anesthesiology Core Review: Part Two Advanced Exam YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259641770 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1135741690 RD 2024/04/23 AB The “myasthenic” disorders all share the primary characteristic of muscle weakness that fluctuates in severity and recovery. These diseases target the three components of synaptic transmission in the neuromuscular junction: presynaptic region, synaptic basal lamina, and postsynaptic receptors. The underlying defects are either autoimmune or genetic in nature.