RT Book, Section A1 Christiansen, Sandy A1 Freeman, Brian S. A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1135739043 T1 Chronic Opioid Dependence and Therapy T2 Anesthesiology Core Review: Part Two Advanced Exam YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259641770 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1135739043 RD 2024/04/20 AB Over the last decade, chronic opioid use has garnered support for the treatment of terminal cancer pain. It also has been prescribed for noncancer pain. However, chronic opioid therapy (COT) is not without risk, or as one might expect, without controversy. Numerous potential ramifications exist, including maintaining nontoxic therapeutic levels that enhance livelihood, minimizing adverse effects, avoiding illicit diversion and abuse, and prescribing within the legal boundaries. Should aberrant use become a problem or if treatment endpoints are not met, alternatives to COT need to be sought for pain management.