RT Book, Section
A1 Diallo, Mofya S.
A2 Freeman, Brian S.
A2 Berger, Jeffrey S.
SR Print(0)
ID 1135738735
T1 Controlled Hypothermia
T2 Anesthesiology Core Review: Part Two Advanced Exam
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9781259641770
LK accessanesthesiology.mhmedical.com/content.aspx?aid=1135738735
RD 2024/04/19
AB Controlled  hypothermia  is  indicated  for  neuroprotection  after  cardiac  arrest,  neonatal  asphyxia,  and  neonatal  encephalopathy,  with  improved  outcome  in  the  intensive  care  unit  setting.  It  has  been  shown  that  decreasing  core  temperature  is  protective  when  there  is  a  risk  of  ischemia  and  hypoxia.  The  brain  has  high  metabolic  demands,  requiring  a  constant  glucose  and  oxygen  supply,  which  make  it  highly  vulnerable  to  injury.  Hypothermia  is  applied  intraoperatively  in  neurosurgical  and  cardiac  surgeries,  both  of  which  are  associated  with  high  risk  of  tissue  hypoxia  and  ischemia.  Cardiac  surgery  requiring  cardiopulmonary  bypass  (CPB)  exposes  multiple  organ  systems,  including  the  brain,  to  the  risk  of  hypoxia  and  ischemia.  Hypothermia  during  CPB  reduces  whole  body  oxygen  consumption.  However,  routine  application  of  induced  hypothermia  continues  to  be  controversial.