TY  - CHAP
M1  - Book, Section
TI  - Acute Kidney Injury and Failure
A1  - Patel, Pritul
A1  - Hosseinian, Leila
A2  - Oropello, John M.
A2  - Pastores, Stephen M.
A2  - Kvetan, Vladimir
PY  - 1
T2  - Critical Care
AB  - KEY  POINTSCurrent  concepts  of  AKI  in  sepsis  indicate  that  systemic  inflammation,  microvascular  dysregulation,  and  mitochondrial  alteration,  leading  to  cell  death  may  be  more  important  than  global  renal  hypoperfusion.Urine  output  and  SCr  are  at  best  surrogate  markers  of  renal  function,  but  can  be  “normal”  in  the  presence  of  renal  dysfunction.Recent  studies  have  identified  new  biomarkers  of  renal  injury  that  can  diagnose  AKI  earlier  than  SCr,  but  these  are  still  in  the  primary  stages  of  clinical  adoption.Prevention  of  contrast-induced  AKI  focuses  on  the  use  of  noniodinated  contrast  media,  minimizing  contrast-media  volume,  avoiding  repeat  exposure  to  contrast  media,  and  expanding  plasma  volume  before  administration  of  contrast  media.The  published  literature  suggests  that  periprocedural  dialysis  has  no  protective  effect  against  CI-AKI.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessanesthesiology.mhmedical.com/content.aspx?aid=1136414640
ER  -