TY - CHAP M1 - Book, Section TI - Hereditary Spherocytosis A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Marciniak, Bruno A1 - Dalens, Bernard J. Y1 - 2006 N1 - T2 - Syndromes: Rapid Recognition and Perioperative Implications AB - Hereditary spherocytosis is characterized by a membrane defect within red blood cells resulting in a shortened survival time. The red cells have low amounts of lipid within the bilayer membrane that lead to an abnormally small amount of surface area. Because the red blood cells are spherocytic, flow through the spleen is difficult, resulting in hemolysis. It is caused by an inherited metabolic defect. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/20 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=58079783 ER -