TY  - CHAP
M1  - Book, Section
TI  - Chapter 68. Long-Term Outcomes after Mechanical Ventilation
A1  - Herridge, Margaret Sutherland
A2  - Tobin, Martin J.
Y1  - 2013
N1  - 
T2  - Principles and Practice of Mechanical Ventilation, 3e
AB  - When  the  first  edition  of  this  book  was  published  in  1994,  the  standard  metric  of  outcome  after  critical  illness  was  28-day  all-cause  mortality.  Since  that  time,  there  has  been  a  revolution  in  the  way  we  view  critical  illness,  its  treatment,  and  its  lasting  effects  both  for  the  patient  and  the  family  caregiver.  The  dramatic  rise  in  the  number  of  longer-term  outcomes  reports  published  over  the  past  5  to  10  years  clearly  reflects  this  point.  It  is  now  apparent  that  most  patients  who  have  survived  an  episode  of  severe  critical  illness  requiring  mechanical  ventilation  will  sustain  some  compromise  in  physical  function  related  to  intensive  care  unit  (ICU)  acquired  weakness  and  a  myriad  of  other  physical  disabilities.1–5  This  acquired  disability  may  be  permanent.5  Patients  may  also  sustain  an  important  new  or  incremental  decline  in  neuropsychological  function,  including  neurocognitive  impairments,  and  neuropsychiatric  or  mood  disorders.6–8  The  constellation  of  muscle,  nerve,  and  brain  dysfunction3,9–13  may  permanently  alter  disposition  for  those  who  were  previously  independent  and  who,  post-ICU,  now  require  assisted  living  or  comprehensive  care.1  ICU-acquired  morbidity  may  result  in  an  additional  cost  burden  in  health  care  utilization  that  is  similar  to  patients  with  chronic  disease,1,5,13–14  and  this  traumatic  life  event  may  completely  erode  the  reserve  of  family  members  and  they  may  also  acquire  new  mood  disorders.15–18  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessanesthesiology.mhmedical.com/content.aspx?aid=57082409
ER  -