TY - CHAP M1 - Book, Section TI - Chapter 41. Complications Associated with Mechanical Ventilation A1 - Provost, Karin A. A1 - El-Solh, Ali A. A2 - Tobin, Martin J. Y1 - 2013 N1 - T2 - Principles and Practice of Mechanical Ventilation, 3e AB - Critically ill patients are at risk of succumbing to their primary disease or the undesired sequelae associated with their therapy. Although frequently lifesaving, the use of positive airway pressure therapy has numerous undesired physiologic and clinical complications. These complications have their origins in the endotracheal or tracheostomy tube, the positive-pressure ventilation (PPV), or from therapies delivered during the care of mechanical ventilation. Other complications may result from coexisting illness or comorbid conditions. Although not commonly recognized as important effects of PPV or positive end-expiratory pressure (PEEP), alterations in organ functions ought to be recognized and addressed accordingly to reduce morbidity and mortality. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/20 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=57074549 ER -