TY - CHAP M1 - Book, Section TI - Botulinum Toxins A1 - Argoff, Charles E. A1 - Smith, Howard A2 - Diwan, Sudhir A2 - Staats, Peter S. PY - 2015 T2 - Atlas of Pain Medicine Procedures AB - Botulinum toxins are neurotoxins produced by the gram-positive, spore-forming, anaerobic bacteria, Clostridium botulinum, as well as C butyricum, C baratii, and C argentinense.1,2 These toxins are the most deadly human neurotoxins known. Clinically, botulism can occur following ingestion of contaminated food or from a wound infection. The clinical signs of botulism include limb paralysis, facial weakness, ophthalmoplegia, dysarthria, dysphagia, dyspnea progressing to respiratory arrest, constipation progressing to ileus, and urinary retention.3C botulinum produces 7 antigenically (immunologically) distinct neurotoxins: A, B, C1, D, E, F, and G. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/23 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1107196150 ER -