TY  - CHAP
M1  - Book, Section
TI  - Complex III Deficiency
A1  - Bissonnette, Bruno
A1  - Luginbuehl, Igor
A1  - Marciniak, Bruno
A1  - Dalens, Bernard J.
PY  - 2006
T2  - Syndromes: Rapid Recognition and Perioperative Implications
AB  - Complex  III  is  located  within  the  inner  membrane  of  the  mitochondria  and  is  the  second  enzyme  in  the  electron  transport  chain  of  the  oxidative  phosphorylation  process.  The  ubiquinol  cytochrome  c  reductase  catalyses  the  electron  transfer  from  succinate  and  nicotinamide  adenine  dinucleotide-linked  dehydrogenases  to  cytochrome  c  within  the  respiratory  chain  located  within  the  inner  membrane  of  the  mitochondria.  The  clinical  features  usually  include  progressive  ataxia,  predominantly  proximal  muscle  weakness,  areflexia,  extensor  plantar  responses,  dementia,  and  concomitant  nonspecific  myopathic  and  neuropathic  changes  in  muscle.  External  ophthalmoplegia,  ptosis  and  cardiomyopathy  are  often  present.  The  most  frequent  clinical  condition  is  Leber  Myopathy.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessanesthesiology.mhmedical.com/content.aspx?aid=58067177
ER  -