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Disorder characterized by galactorrhea and amenorrhea.

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Amenorrhea-Galactorrhea-Hyperprolactinemia Syndrome.

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  • Type I = Chiari-Frommel Syndrome: persistent AGS after giving birth.
  • Type II = Ahumada-Del Castillo Syndrome (Argonz del Castillo-Ahumada Syndrome; Amenorrhea-Galactorrhea FSH Decrease Syndrome; Nonpuerperal Galactorrhea-Amenorrhea Syndrome): AGS not associated with pregnancy. Estrogen deficiency and decreased urinary gonadotropin levels.
  • Type III = Forbes-Albright Syndrome: AGS caused by chromophobe prolactin-producing adenoma of the pituitary.

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Autosomal dominant.

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Tumors resembling chromophobe adenomas of the pituitary gland with eosinophilic granulation on tetrachrome staining.

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Secondary amenorrhea with galactorrhea. Enlargement of the sella turcica.

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No known specific anesthetic considerations for this syndrome.

Rimoin DL, Schimke RN: Genetic Disorders of the Endocrine Glands. St. Louis, CV Mosby, 1971.

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