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Contributors

Editors

Jesse B. Hall, MD
Director of Critical Care Services
Professor of Medicine and of Anesthesia and Critical Care
Section of Pulmonary and Critical Care
University of Chicago
Chicago, Illinois

Gregory A. Schmidt, MD
Director, Critical Care Services
Professor of Medicine and of Anesthesia and Critical Care
Section of Pulmonary and Critical Care
University of Chicago
Chicago, Illinois

Lawrence D. H. Wood, MD, PhD
Faculty Dean of Medical Education
University of Chicago Pritzker School of Medicine
Professor of Medicine and of Anesthesia and Critical Care
Section of Pulmonary and Critical Care Medicine
University of Chicago
Chicago, Illinois

Associate Editors

Jameel Ali, MD, M Med Ed, FRCS[C], FACS
Professor of Surgery, University of Toronto
Toronto, Ontario, Canada
National ATLS faculty and Educator
American College of Surgeons Committee on Trauma
Toronto, Ontario, Canada
Chapters 87, 88, 92, 95

Keith R. Walley, MD
Associate Professor of Medicine
University of British Columbia
Pulmonary Research Laboratory
Vancouver, British Columbia, Canada

CONTRIBUTORS

BENJAMIN S. ABELLA, MD, MPhil
Department of Medicine
Section of Emergency Medicine
University of Chicago
Chicago, Illinois
Chapters 15, 16

VENKATESH AIYAGARI, MD
Assistant Professor of Neurology and Neurological Surgery
Washington University School of Medicine
St. Louis, Missouri
Chapter 63

RICHARD K. ALBERT, MD
Professor
Department of Medicine
University of Colorado
Health Sciences Center
Chief of Medicine
Denver Health Medical Center
Denver, Colorado
Chapter 41

Jameel Ali, MD, M Med Ed, FRCS[C], FACS
Professor of Surgery, University of Toronto
Toronto, Ontario, Canada
National ATLS faculty and Educator
American College of Surgeons Committee on Trauma
Toronto, Ontario, Canada
Chapters 87, 88, 92, 95

JASON ALVARADO, BA
Department of Medicine
Section of Emergency Medicine
University of Chicago
Chicago, Illinois
Chapter 15

DEREK C. ANGUS, MD, MPH
Professor and Vice Chair
Department of Critical Care Medicine
Director, The CRISMA Laboratory
University of Pittsburgh
School of Medicine
Pittsburgh, Pennsylvania
Chapter 2

FRED Y. AOKI, MD
Professor of Medicine
Medical Microbiology, Pharmacology and Therapeutics
University of Manitoba
Winnipeg, Manitoba, Canada
Chapter 45

JOSEPH J. AUSTIN, MD
Cardiothoracic Surgery
Overlake Hospital Medical Center
Bellevue, Washington
Chapter 30

GEORGE BALTOPOULOS, MD
Professor of Critical Care and Pulmonary Diseases
University of Athens School of Nursing
Director
Athens University School of Nursing Intensive
Care Unit at KAT Hospital
Athens, Greece
Chapter 23

JOSEPH M. BARON, MD
Section of Hematology/Oncology
University of Chicago
Chicago, Illinois
Chapter 69

BEVERLY W. BARON, MD
Department of Pathology
Blood Banking/Transfusion Medicine
University of Chicago
Chicago, Illinois
Chapter 69

WALTER G. BARR, MD
Professor of Medicine
Director
Training Program
Division of Rheumatology
Northwestern University Feinberg
School of Medicine
Chicago, Illinois
Chapter 104

SARICE L. BASSIN, MD
Neurointensivist
Neuroscience Institute
Critical Care Neurology and Stroke
Queen’s Medical Center
Honolulu, Hawaii
Chapter 64

LANCE B. BECKER, MD
Professor of Clinical Medicine
Section of Emergency Medicine
University of Chicago
Chicago, Illinois
Chapters 15, 16

ISRAEL BELENKIE, MD
Professor of Medicine
Departments of Medicine and Cardiac Sciences
Libin Cardiovascular Institute of Alberta
University of Calgary
Calgary, Alberta, Canada
Chapter 28

THOMAS P. BLECK, MD
The Louise Nerancy Eminent Scholar in Neurology and
Professor of Neurology, Neurological Surgery, and Internal Medicine
Director, Neuroscience Intensive Care Unit
The University of Virginia
Charlottesville, Virginia
Chapter 64

IRA J. BLUMEN, MD
Professor, Section of Emergency Medicine
Department of Medicine
University of Chicago
Chicago, Illinois
Program and Medical Director
University of Chicago Aeromedical Network (UCAN)
University of Chicago Hospitals
Chicago, Illinois
Chapter 7

JOHN BOHNEN, MD, FRCSC, FACS
Director
Postgraduate Surgical Education
Associate Professor
Department of Surgery
University of Toronto
Toronto, Ontario, Canada
Chapter 89

ERIC J. BOW, MD
Sections of Infectious Diseases and
Haematology/Oncology
Professor and Head, Section of Haematology/Oncology
Department of Internal Medicine
University of Manitoba
Head, Department of Medical Oncology and Haematology
Director, Infection Control Services, Cancer Care
Manitoba
Winnipeg, Manitoba, Canada
Chapter 47

MICHAEL BRESLOW, MD
Executive Vice President, Research and Development
VISICU, Inc.
Baltimore, Maryland
Chapter 8

LAURENT BROCHARD
Professor of Intensive Care Medicine
Medical Intensive Care Unit
Hôpital Henri Mondor
Assistance Publique
Hôpitaux de Paris
Université Paris
Créteil, France
Chapter 33

STEVEN D. BROWN, MD
Professor and Chief Medical Officer
University of Texas Health Center at Tyler
Tyler, Texas
Chapter 112

JOHN B. BUSE, MD, PhD
Associate Professor of Medicine
Chief, Division of General Medicine and Clinical Epidemiology
Director, Diabetes Care Center
University of North Carolina
School of Medicine
Chapel Hill, North Carolina
Chapter 78

MARK B. CARR, MD
Baptist Hospital
Nashville, Tennessee
Chapter 49

SHANNON S. CARSON, MD
Assistant Professor
Division of Pulmonary and Critical Care Medicine
University of North Carolina
Chapel Hill, North Carolina
Chapter 18

JEAN CHASTRE, MD
Reanimation Medicale
Groupe Hospitalier Pitie Salpetriere
Institut de Cardiologie
Paris, France
Chapter 43

ANTHONY W. CHOW, MD
Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of British Columbia And Vancouver Hospital
Health Sciences Center
Director, MD/PhD Program, University of British Columbia
Vancouver, British Columbia
Chapter 54

JASON D. CHRISTIE, MD, Ms
Assistant Professor of Medicine
Division of Pulmonary, Allergy, and Critical Care Medicine
Assistant Professor of Epidemiology
Department of Biostatistics and Epidemiology
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
Chapter 38

GLENN C. COBBS, MD
Professor Emeritus of Medicine
University of Alabama at Birmingham
Birmingham, Alabama
Chapter 49

JOHN M. CONLY, MD
Head
Department of Medicine
University of Calgary
Calgary Health Region
Foothills Medical Centre
Calgary, Alberta, Canada
Chapters 50, 55

DEBORAH COOK, MD
Professor of Medicine and Clinical Epidemiology and Biostatistics
Chair
Critical Care Medicine
McMaster University
Hamilton, Ontario, Canada
Chapter 10

THOMAS CORBRIDGE, MD
Associate Professor of Medicine
Director, Medical Intensive Care
Northwestern School of Medicine
Chicago, Illinois
Chapters 40, 42, 102, 103

MICHAEL T. COUGHLIN, MA
Project Manager, The CRISMA Laboratory
Department of Critical Care Medicine
University of Pittsburgh School of Medicine
Pittsburgh, Pennsylvania
Chapter 2

DAVID C. CRONIN II, MD, PhD
Assistant Professor of Surgery
Section of Transplantation
University of Chicago
Chicago, Illinois
Chapter 83

STEPHEN W. CRAWFORD, MD
United States Navy Medical Corps
Pulmonary Medicine
Naval Medicine Center San Diego
San Diego, California
Chapter 73

FRANK D’OVIDIO, MD, PhD
Thoracic Surgery and Lung Transplantation
Toronto General Hospital
University of Toronto
Toronto, Ontario, Canada
Chapter 91

ROBERT H. DEMLING, MD
Burn Center
Brigham and Women’s Hospital
Boston, Massachusetts
Professor of Surgery
Harvard Medical School
Boston, Massachusetts
Chapters 98, 99, 100

APURVA A. DESAI, MD
Assistant Professor of Medicine
Section of Hematology/Oncology
The University of Chicago Medical Center
Chicago, Illinois
Chapter 74

LESLIE DeSANTI, RN
Burn Research
Brigham & Women’s Hospital
Boston, Massachusetts
Chapters 98, 99, 100

MICHAEL N. DIRINGER, MD
Associate Professor of Neurology, Neurosurgery and Anesthesiology
Washington University School of Medicine
Director, Neurology/Neurosurgery
Intensive Care Unit
Barnes-Jewish Hospital
Department of Neurology
St. Louis, Missouri
Chapter 63

IVOR S. DOUGLAS, MD, MRCP (UK)
Assistant Professor
Pulmonary and Critical Care Medicine
Director
Medical Intensive Care
Denver Health
University of Colorado Health Sciences Center
Denver, Colorado
Chapter 39

TONY T. DREMSIZOV
Senior Research Specialist
CRISMA Laboratory
Department of Critical Care Medicine
University of Pittsburgh
Pittsburgh, Pennsylvania
Chapter 2

ELI D. EHRENPREIS, MD
Assistant Professor of Medicine
Rush Presbyterian St. Luke’s Medical Center
Adult Care Specialists
Chicago, Illinois
Chapter 81

E. WESLEY ELY, MD, MPH
Associate Professor of Medicine
Division of Allergy, Pulmonary, and Critical Care
Vanderbilt University Medical Center
Associate Director of Research
Tennessee Valley Veterans Administration Geriatric
Research Education and Clinical Center
Nashville, Tennessee
Chapters 46, 62

JEAN-YVES FAGON, MD, PhD
Professor of Medicine
Service de Réanimation Médicale
Hôpital Européen Georges Pompidou
Paris, France
Chapter 43

J. CHRISTOPHER FARMER, MD
Professor of Medicine
Division of Pulmonary and Critical Care Medicine
Program in Translational Immunovirology and Biodefense
Mayo Clinic
Rochester, Minnesota
Chapter 9

SUSAN FISHER-HOCH, MD
Professor
Division of Epidemiology
University of Texas School of Public Health at Brownsville
Brownsville, Texas
Chapter 60

GERASIMOS S. FILIPPATOS, MD
Critical Care Unit and Heart Failure Unit
Evangelismos General Hospital
Chairman
Working Group on Acute Cardiac Care
European Society of Cardiology
Athens, Greece
Chapter 23

GINI F. FLEMING, MD
Associate Professor, Department of Medicine
Section on Hematology, Oncology
The University of Chicago Medical Center
Chicago, Illinois
Chapter 74

RODNEY J. FOLZ, MD, PhD
Associate Professor of Medicine
Assistant Research Professor of Cell Biology
Division of Pulmonary, Allergy, and Critical Care Medicine
Duke University Medical Center
Durham, North Carolina
Chapter 73

NATHAN B. FOUNTAIN, MD
Associate Professor of Neurology
Director
FE Dreifuss Comprehensive Epilepsy Program
University of Virginia
Charlottesville, Virginia
Chapter 64

JEFFREY I. FRANK, MD, FAAN, FAHA
Director
Neuromedical/Neurosurgical Intensive Care
Associate Professor
Neurology and Surgery
University of Chicago
Chicago, Illinois
Chapters 65, 67

JOHN C. GALBRAITH, MD
Medical Director
Dynacare Kasper Medical Laboratories
Edmonton, Alberta, Canada
Chapter 53

ALLAN GARLAND, MD
Associate Professor of Medicine
Case Western Reserve University School of Medicine
Director, Medical Intensive Care Unit
Division of Pulmonary and Critical Care Medicine
MetroHealth Medical Center
Cleveland Ohio
Chapter 3

BRIAN GEHLBACH, MD
Assistant Professor of Medicine
Section of Pulmonary and Critical Care
University of Chicago
Chicago, Illinois
Chapters 14, 34, 109

ANNE M. GILLIS, MD, FRCPC
Professor of Medicine
University of Calgary
Medical Director of Pacing and Electrophysiology
Department of Cardiac Sciences
Calgary Health
University of Calgary
Calgary, Alberta, Canada
Chapter 24

MARK T. GLADWIN, MD
Chief
Vascular Therapeutics Section
Cardiovascular Branch
National Heart, Lung, and Blood Institute
Critical Care Medicine Department
Clinical Center
National Institutes of Health
Bethesda, Maryland
Chapter 108

LAWRENCE TIM GOODNOUGH, MD
Department of Pathology and Medicine
Stanford University
Stanford, California
Chapter 70

LAWRENCE J. GOTTLIEB, MD
Professor of Surgery
Director of Burn and Complex Wound Center
University of Chicago
Chicago, Illinois
Chapter 97

JENNIFER E. GOULD, MD
Assistant Professor of Radiology
Washington University School of Medicine
St. Louis, Missouri
Chapter 101

RICHERT E. GOYETTE, MD
Consultant
Knoxville, Tennessee
Chapter 46

JOHN T. GRANTON, MD
Program Director
Critical Care Medicine
University of Toronto
Director, Pulmonary Hypertension Program
University Health Network
Toronto, Ontario, Canada
Chapters 37, 90

PERRY R. GRAY, MD
Critical Care Site Manager
Director
SICU
Health Sciences Center
Winnipeg, Manitoba, Canada
Chapter 59

GENEVIÈVE GRÉGOIRE, MD, FRCPC
Assistant Professor of Medicine
University of Montreal
Intensivist
Department of Medicine
Hôpital du Sacre-Couer de Montreal
Montreal, Quebec, Canada
Chapter 6

JESSE B. HALL, MD
Professor, Medicine, Anesthesia and Critical Care
Section of Pulmonary and Critical Care Medicine
Department of Medicine
University of Chicago
Chicago, Illinois
Chapters 1, 36, 40, 44, 105

MICHAEL J. HALL, MD
Section of Hematology and Oncology
Department of Medicine
University of Chicago
Chicago, Illinois
Chapter 71

NICOLA A. HANANIA, MD
Assistant Professor of Medicine
Pulmonary and Critical Care Medicine
Director, Asthma Clinical Research Center
Baylor College of Medicine
Houston, Texas
Chapters 110, 111

DENIS W. HARKIN, MD, FRCS
Vascular Fellow
Department of Surgery
University of Toronto
Toronto, Ontario, Canada
Chapter 86

MARGARET S. HERRIDGE, MSc, MD, FRCPC, MPH
Pulmonary and Critical Care Medicine
University Health Network
Assistant Professor of Medicine
Interdepartmental Division of Critical Care
University of Toronto
Toronto, Ontario, Canada
Chapter 19

DAREN K. HEYLAND, MD, MSc, FRCPC
Associate Professor
Kingston General Hospital
Kingston, Ontario, Canada
Chapter 11

PHILIP C. HOFFMAN, MD
Professor of Medicine
Section of Hematology/Oncology
The University of Chicago
Chicago, Illinois
Chapter 72

STEVEN M. HOLLENBERG, MD
Director
Coronary Care Unit
Cooper University Hospital
Professor of Medicine
Robert Wood Johnson Medical School/ University of Medicine and Dentistry of New Jersey
Camden, New Jersey
Chapter 25

CHERYL L. HOLMES, MD
Clinical Instructor
Department of Medicine
University of British Columbia
Vancouver, British Columbia
Director, Critical Care Medicine
Department of Medicine
Kelowna General Hospital
Kelowna, British Columbia, Canada
Chapter 6

RAMONA O. HOPKINS, PhD
Psychology Department and Neuroscience Center
Brigham Young University
Provo, Utah
and Department of Medicine
Pulmonary and Critical Care Divisions
LDS Hospital
Salt Lake City, Utah
Chapter 19

GARTH JOHNSON, MD
Professor of Surgery
University of Ottawa
Division of Orthopedic Surgery
Ottawa Hospital
Ottawa, Ontario, Canada
Chapter 94

MARSHALL B. KAPP, JD, MPH
Arthur W. Grayson Distinguished Professor of Law
and Medicine
Southern Illinois University
School of Law
Carbondale, Illinois
Chapter 5

ELIAS KARAMBATSOS, MD
Physician
Cellular and Molecular Biology
Naxos, Greece
Chapter 23

MANOJ KARWA, MD
Assistant Professor of Medicine
Critical Care Medicine
Montefiore Medical Center
Albert Einstein College of Medicine
Bronx, New York
Chapter 61

GREGORY J. KATO, MD
Investigator
Critical Care Medicine Department
Clinical Center
Vascular Therapeutics Section
Cardiovascular Branch
National Heart, Lung, and Blood Institute
National Institutes of Health
Bethesda, Maryland
Chapter 108

DAVID C. KAUFMAN, MD
Associate Professor
Department of Surgery
Strong Memorial Hospital
University of Rochester
Rochester, New York
Chapter 77

JOHN A. KELLUM, MD
Associate Professor
Departments of Critical Care Medicine and Medicine
University of Pittsburgh
Pittsburgh, Pennsylvania
Chapter 77

SHAF KESHAVJEE, MD, MSc, FRCSC, FACS
Head
Division of Thoracic Surgery
Director
Toronto Lung Transplant Program
Professor and Chair
Division of Thoracic Surgery
University of Toronto
Toronto General Hospital
Toronto, Ontario, Canada
Chapter 91

ANDREW J. KITCHING, MB, ChB
Consultant Anaesthetist
Royal Berkshire Hospital
London Road
Reading, United Kingdom
Chapter 77

MARIN H. KOLLEFF, MD
Associate Professor of Medicine
Washington University School of Medicine
Director
Medical Intensive Care Unit
Director
Respiratory Care Services
Barnes-Jewish Hospital
St. Louis, Missouri
Chapter 4

JOHN P. KRESS, MD
Assistant Professor of Medicine
Section of Pulmonary and Critical Care
University of Chicago
Chicago, Illinois
Chapters 12, 14, 109

VIDYA KRISHNAN
Pulmonary and Critical Care Division
Johns Hopkins University School of Medicine
Baltimore, Maryland
Chapter 103

SANJAY KULKARNI, MD
Assistant Professor
Section of Organ Transplantation and Immunology
Yale University School of Medicine
New Haven, Connecticut
Chapter 83

VLADIMIR KVETAN, MD
Professor of Anesthesiology and Clinical Medicine
Associate Professor of Surgery
Director of Critical Care Medicine Service and Fellowship, Critical Care Medicine
Montefiore Medical Center
Albert Einstein Medical Center
Bronx, New York
Chapter 61

MARIO E. LACOUTRE, MD
Resident, Dermatology Section University of Chicago
University of Chicago
Chicago, Illinois
Chapter 107

ELIZABETH B. LAMONT, MD, MS
Assistant Professor of Medicine
Massachusetts General Hospital Cancer Center
Harvard Medical School
Boston, Massachusetts
Chapter 72

PAUL N. LANKEN, MD
Professor of Medicine
Pulmonary, Allergy, and Critical Care Division
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
Chapter 38

RICHARD A. LARSON, MD
Professor of Medicine
Section of Hematology and Oncology
Department of Medicine
Cancer Research Center
University of Chicago
Chicago, Illinois
Chapter 71

ANNE E. LAUMANN, MBChB, MRCP (UK)
Associate Professor of Dermatology
Northwestern University
Chicago, Illinois
Chapter 107

JAMES W. LEATHERMAN, MD
Associate Professor of Medicine
University of Minnesota
Division of Pulmonary and
Critical Care Medicine
Hennepin County Medical Center, Minneapolis
Chapters 13, 66

RAPHAEL C. LEE, MD, ScD
Professor of Surgery, Dermatology, Molecular Medicine, and Organismal Biology and Anatomy
Director, Electrical Trauma Program
Director, Program for Research in Cellular Repair
University of Chicago
Chicago, Illinois
Chapter 97

ALLAN S. LIEW, MD, FRCSC
Division of Orthopedic Surgery
Ottawa Hospital
Ottawa, Ontario, Canada
Chapter 96

R. BRUCE LIGHT, MD
Professor of Medicine and Medical Microbiology
University of Manitoba
Winnipeg, Manitoba, Canada
Chapter 51

THOMAS F. LINDSAY, MD, FRCSC, FACS
Chair
Division of Vascular Surgery
Associate Professor of Surgery
University of Toronto
Toronto, Ontario, Canada
Chapter 86

> RAGHU S. LOGANATHAN, MD
Fellow in Critical Care Medicine
Montefiore Medical Center
Albert Einstein College of Medicine
Bronx, New York
Chapter 61

JOHN M. LUCE, MD
Professor of Medicine and Anesthesia
University of California–San Francisco
Associate Medical Director, Medical and Surgical
Intensive Care Units
Medical Director, Quality, Utilization, and Risk Management
San Francisco General Hospital
San Francisco, California
Chapters 17, 68

JUDITH A. LUCE, MD
Clinical Professor of Medicine
University of California–San Francisco
Director
Oncology Services
San Francisco General Hospital
Chapter 68

CONSTANTINE A. MANTHOUS, MD
Director, Medical Intensive Care
Bridgeport Hospital
Associate Clinical Professor of Medicine
Yale University School of Medicine
Bridgeport, Connecticut
Chapter 44

PAUL MARIK, MD, FCCM, FCCP
Director
Pulmonary and Critical Care
Professor of Medicine
Thomas Jefferson University
Philadelphia, Pennsylvania
Chapter 79

WILLIAM A. MARINELLI, MD
Associate Professor of Medicine
University of Minnesota
Medical Director, Respiratory Care
Hennepin County Medical Center
Minneapolis, Minnesota
Chapter 66

JOHN J. MARINI, MD
Professor of Medicine
University of Minnesota
Director of Translational Research
HealthPartners Medical Group
Minneapolis/St. Paul, Minnesota
Chapter 13

TIMOTHY M. McCASHLAND, MD
Associate Professor of Medicine
Section of Gastroenterology and Hepatology
University of Nebraska
Omaha, Nebraska
Chapter 82

STEVE A. McCLAVE, MD
Professor of Medicine
Division of Gastroenterology/Hepatology
Director of Clinical Nutrition
University of Louisville School of Medicine
Louisville, Kentucky
Chapter 11

JOHN F. McCONVILLE, MD
Assistant Professor of Medicine
University of Chicago
Chicago, Illinois
Chapter 12

DONNA I. McRITCHIE, MD, MSc, FRCSC
Assistant Professor of Surgery
University of Toronto
Medical Director
Clinical Care
North York General Hospital
Toronto, Ontario, Canada
Chapter 91

PAUL MICHEL MERTES, MD, PhD
Professor and Chair
Service d’Anésthesie-réanimation
CHU de Nancy
Hôpital Central
Nancy, France
Chapter 106

NUALA J. MEYER, MD
Fellow
Pulmonary and Critical Care
University of Chicago
Chicago, Illinois
Chapter 27

BABAK MOKHLESI, MD
Assistant Professor of Medicine
Division of Pulmonary and Critical Care Medicine
John H. Striger Jr. Hospital of Cook County/Rush
University Medical Center
Chicago, Illinois
Chapter 102

JULIO S. G. MONTANER, MD
Professor of Medicine & Chair in AIDS Research
St. Paul’s Hospital/University of British Columbia
Vancouver, British Columbia, Canada
Chapter 48

BUSI MOOKA, MD, MRCPI
Specialist Registrar
Department of Infectious Diseases
Mater Hospital
Dublin, Ireland
Chapter 56

JONATHAN MOSS, MD, PhD
Professor and Vice Chairman for Research
Dept. of Anesthesia & Critical Care
Professor of the College
Chairman, Institutional Review Board
University of Chicago
Chicago, Illinois
Chapter 106

RICHARD J. MOULTON, MD, FRCSC
Medical Director
Trauma and Neurosurgery Program
St. Michael’s Hospital
Associate Professor of Surgery
University of Toronto
Toronto, Ontario, Canada
Chapter 93

PATRICK MURRAY, MD
Associate Professor of Anesthesia, Critical Care and Medicine (Nephrology)
University of Chicago
Chicago, Illinois
Chapters 75, 76, 102, 103

ROBERT MUSTARD, MD
Assistant Professor of Surgery
St. Michael’s Hospital
Toronto, Ontario, Canada
Chapter 89

MARKKU S. NIEMINEN, MD
Professor and Chief
Division of Cardiology
University Central Hospital
Chairman
Task Force on Acute Heart Failure
European Society of Cardiology
Helsinki, Finland
Chapter 23

MICHAEL F. O’CONNOR, MD
Associate Professor
Department of Anesthesia and Critical Care
Department of Medicine
Section of Pulmonary and Critical Care
University of Chicago
Chicago, Illinois
Chapters 35, 105

ANDRANIK OVASSAPIAN
Professor
Department of Anesthesia and Critical Care
The University of Chicago
Chicago, Illinois
Chapter 35

JOSEPH E. PARRILLO, MD
Professor of Medicine
Robert Wood Johnson Medical School
University of Medicine and Dentistry of New Jersey
Head
Division of Cardiovascular Disease and Critical Care Medicine
Director
Cooper Heart Institute
Director
Cardiovascular and Critical Care Services
Cooper University Hospital
Camden, New Jersey
Chapter 25

> CLAUDE A. PIANTADOSI, MD
Professor of Medicine
Duke University Medical Center
Durham, North Carolina
Chapter 112

DANIEL PICUS, MD
Professor of Radiology and Surgery
Department of Radiology
Washington University School of Medicine
St. Louis, Missouri
Chapter 101

LAWRENCE H. PITTS, MD
Professor of Neurosurgery
University of California–San Francisco
San Francisco, California
Chapter 93

PETER PHILLIPS, MD
Head, Infectious Diseases
St. Paul’s Hospital
Vancouver, British Columbia, Canada
Chapter 48

WILLIAM J. POWERS, MD
Professor of Neurology, Neurological Surgery and Radiology
Head, Cerebrovascular Section
Department of Neurology
Washington University School of Medicine
St. Louis, MO
Chapter 63

KENNETH S. POLONSKY, MD
Adolphus Busch Professor
Head
Department of Internal Medicine
Washington University School of Medicine
St. Louis, Missouri
Chapter 78

STEVEN M. RANKIN, MD
Department of Nephrology
St. Joseph Hospital
Pontiac, Michigan
Chapter 76

BHARATHI REDDY, MD
Assistant Professor of Medicine
Section of Nephrology
University of Chicago
Chicago, Illinois
Chapter 75

SAMUEL REFETOFF, MD
Frederick H. Rawson Professor Emeritus
Endocrinology Section
Department of Medicine and Pediatrics
Director
Endocrinology Laboratory
University of Chicago
Chicago, Illinois
Chapter 80

JOHN A. ROBINSON, MD
Professor of Medicine and Microbiology
Director
Therapeutic Apheresis
Stritch School of Medicine
Loyola University Medical Center
Chicago, Illinois
Chapter 104

GRAEME ROCKER, MD
Professor of Medicine
Dalhousie University
Halifax, Nova Scotia, Canada
President, Canadian Critical Care Society
Halifax, Nova Scotia, Canada
Chapter 10

AXEL J. ROSENGART, MD, PhD
Assistant Professor
Departments of Neurology and Surgery
Assistant Director
Neuromedical/Neurosurgical Intensive Care
University of Chicago
Chicago, Illinois
Chapters 65, 67

JAMES A. RUSSELL, MD
Intensivist, St. Paul’s Hospital
Principal Investigator, James Hogg Centre
for Cardiovascular & Pulmonary Research
Professor of Medicine, Critical Care Medicine
University of British Columbia
Vancouver, British Columbia, Canada
Chapters 6, 48

DAMON C. SCALES, MD, FRCPC
Clinical Associate
Department of Critical Care
St. Michael’s Hospital
Toronto, Ontario, Canada
Chapter 90

WILLIAM MICHAEL SCHELD, MD
Bayer-Gerald N. Mandell Professor of Infectious Diseases
Professor of Internal Medicine
Clinical Professor of Neurosurgery
Co-Director of the Center for Global Health
University of Virginia School of Medicine
Charlottesville, Virginia
Chapter 52

THOMAS D. SCHIANO, MD
Associate Professor of Medicine
Division of Liver Diseases
Mount Sinai Medical Center
New York, New York
Chapter 81

GREGORY A. SCHMIDT, MD
Section of Pulmonary and Critical Care Medicine
Department of Medicine
University of Chicago
Chicago, Illinois
Chapters 1, 36

B.D. SCHOUTEN, MD
Sepsis Critical Care Research Office
The Wellesley Hospital
Toronto, Ontario, Canada
Chapter 89

GERARD J. SHEEHAN, MB
Consultant Physician in Infectious Diseases
Mater Misericordiae Hospital
Dublin, Ireland
Chapter 56

JAMES M. SIZEMORE, JR., MD, MSPH
Assistant Professor of Medicine
Division of Infectious Diseases
University of Alabama–Birmingham
Birmingham, Alabama
Chapter 49

ARTHUR S. SLUTSKY, MD
Professor of Medicine
Surgery and Biomedical Engineering Division
Director, Interdepartmental Division of Critical Care Medicine
University of Toronto
Vice President, Research
St. Michael’s Hospital
Queen Wing
Toronto, Ontario, Canada
Chapter 37

MATTHEW J. SORRENTINO, MD
Associate Professor of Medicine
University of Chicago Pritzker
School of Medicine
Department of Medicine
Section Cardiology
Chicago, Illinois
Chapter 29

MARY E. STREK, MD
Associate Professor of Medicine and Clinical Pharmacology
Section of Pulmonary and Critical Care Medicine
University of Chicago
Chicago, Illinois
Chapter 105

RAM M. SUBRAMANIAN, MD
Fellow, Sections of Pulmonary & Critical Care
Medicine and Gastroenterology
Department of Medicine
University of Chicago
Chicago, Illinois
Chapter 82

KEITH M. SULLIVAN, MD
James B.Wyngaarden Professor of Medicine
Director, Long-Term Follow-up and Information Research Program
Division of Cellular Therapy
Duke University Medical Center
Durham, North Carolina
Chapter 73

BRYCE TAYLOR, MD, FRCSC, FACS
Surgeon-in-Chief
University Health Network
Professor and Chair
Department of Surgery
University of Toronto
Toronto, Ontario, Canada
Chapter 85

FRANK THOMAS, MD, MBA
Medical Director IHC Life Flight, Adult Services
Co-Director Shock Trauma ICU, LDS Hospital
Clinical Professor of Medicine
University of Utah School of Medicine
Critical Care Medicine
LDS Hospital
Salt Lake City, Utah
Chapter 7

JOEL M. TOPF, MD
Department of Nephrology
St. John’s Hospital
Detroit, Michigan
Chapter 76

ALLAN R. TUNKEL, MD, PhD
Professor of Medicine
Associate Dean for Admissions
Drexel University College of Medicine
Philadelphia, Pennsylvania
Chapter 52

JOHN V. TYBERG, MD, PhD
Professor of Medicine and Physiology & Biophysics
Departments of Medicine and Cardiac Sciences
Libin Cardiovascular Institute of Alberta
University of Calgary
Calgary, Alberta, Canada
Chapter 28

D. LORNE TYRRELL, MD, PhD
Professor
Department of Medical Microbiology and Immunology
University of Alberta
Edmonton, Alberta, Canada
Chapter 53

TERRY VANDEN HOEK, MD
Associate Professor of Clinical Medicine
Section of Emergency Medicine
University of Chicago
Chicago, Illinois
Chapters 15, 16

ROBERT VERITY, MD
Dynacare Kasper Medical Laboratories
Edmonton, Alberta, Canada
Chapter 53

KEITH R. WALLEY, MD
Professor of Medicine
University of British Columbia
Vancouver, Canada
Chapters 21, 22

JEFFREY G. WALLS, MD
Staff Physician
Pulmonary and Critical Care
Presbyterian Hospital
Charlotte, North Carolina
Chapter 9

FERGUS WALSH
Consultant Anesthetist
Cork University Hospital
Clinical Lecturer
University College Cork
Cork, Ireland
Chapter 88

DAVID A. WARRELL, MA, DM, DSc
Professor of Tropical Medicine and Infectious Diseases
Founding Director of the Centre of Tropical Medicine (Emeritus)
University of Oxford
Oxford
United Kingdom
Chapter 58

DAVID K. WARREN, MD
Assistant Professor
Division of Infectious Diseases
Department of Medicine
Washington University School of Medicine
Hospital Epidemiologist
Barnes-Jewish Hospital
Saint Louis, Missouri
Chapter 4

STEPHEN G. WEBER, MD, MS
Assistant Professor of Medicine
Section of Infectious Diseases
Hospital Epidemiologist
Director, Infection Control Program
The University of Chicago
Chicago, Illinois
Chapter 57

ROY E. WEISS, MD, PhD, FACP
Professor of Medicine
Director
Clinical Research Center
Department of Medicine
University of Chicago
Chicago, Illinois
Chapter 80

MICHAEL JUDE WELSCH, MD
Resident
Section of Dermatology
University of Chicago
Chicago, Illinois
Chapter 107

DAVID WILLIAMS, MD
Emergency Physician
Intermountain Health Care
Salt Lake City, Utah
Chapter 7

LAWRENCE D.H. WOOD, MD, PhD
Professor of Medicine
Section of Pulmonary and Critical Care
Medicine
Department of Medicine
University of Chicago
Chicago, Illinois
Chapters 1, 20, 42

GARY P. ZALOGA, MD
Medical Director, Methodist Research Institute
Clinical Professor of Medicine
Indiana University
Indianapolis, Indiana
Chapter 79

JANICE L. ZIMMERMAN, MD
Professor of Medicine
Baylor College of Medicine
Director, Medicine Emergency Services
Associate Chief, Medicine Service
Ben Taub General Hospital
Houston, Texas
Chapters 110, 111

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